Welcome to the best 1000 Islands Boutique Hotels in Gananoque, ON. The Gananoque Inn & Spa is a great spot in the heart of the 1000 Islands for a conference, wedding, boutique hotel or a weekend getaway! Your amazing 1000 Islands vacation beginnings here! Offering more than some other lodging in Gananoque, the Quality Inn and Suites flaunts an acclaimed nearby café, extensive whirlpool suites and the most elevated levels of administration and neatness.